Carafate and levothyroxine Interactions

The majority of patients had underlying medical conditions that may predispose to bezoar formation (such as delayed gastric emptying) or were receiving concomitant enteral tube feedings. It’s important to note that all medical situations are unique, and management approaches should be tailored to individual circumstances. Patients should always consult their healthcare provider for personalized advice and guidance on managing drug interactions effectively.

• This interaction could result in very serious and potentially life-threatening consequences.
• The interactionsgenerally can be circumvented byappropriate adjustment of the dosingtimes of the levothyroxine relative tothe binding agents.
• Carafate (sucralfate) is an anti-ulcer medication used to treat duodenal ulcers.
• Foran electronic version of this article,including references if any, visit
• Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Interactions between your drugs

It may take 2 to 8 weeks before you receive the full benefit of taking Carafate. Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Your doctor may adjust your dose based on your blood sugar levels. Safety and effectiveness in pediatric patients have not been established.

Berberine With Femara Interaction Details

Sucralfate is only minimally absorbed from the gastrointestinal tract. The small amounts of the sulfated disaccharide that are absorbed are excreted primarily in the urine. This document does not contain all possible side effects and others may occur.

• Safety and effectiveness in pediatric patients have not been established.
• These foods should be avoided within several hours of dosing if possible.
• There are approximately 14 to 16 mEq of acid-neutralizing capacity per 1 g dose of sucralfate.
• Chronic oral toxicity studies of 24 months’ duration were conducted in mice and rats at doses up to 1 g/kg (12 times the human dose).
• In studies involving over 2700 patients treated with sucralfate, adverse effects were reported in 129 (4.7%).

Cases of bronchospasm, laryngeal edema and respiratory tract edema have been reported with an unknown oral formulation of sucralfate. This interaction has the potential to worsen your medical condition or alter the effectiveness of your treatment. It’s important that you are monitored closely and you potentially may need to make adjustments in your treatment plan or drug dosage to maintain optimal health. Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Levothyroxine with Sucralfate Interaction Details

It may be necessary to change a medication or dosage to prevent harm. Levothyroxine is a man-made form of the human thyroid hormone called T4. It is given to people who do not produce enough of their own thyroid hormone (hypothyroidism). Sucralfate can heal an active ulcer, but it will not prevent future ulcers from occurring. In a multicenter, double-blind, placebo-controlled study of synthroid isagenix CARAFATE Oral Suspension, a dosage regimen of 1 gram (10 mL) four times daily was demonstrated to be superior to placebo in ulcer healing.

Consequently, TSH levels should be monitored approximately 6 to 8 weeks after initiating treatment and dose changes. In general, it is not necessary to discontinuethe drug that is reducing levothyroxineabsorption (see box above right). The interactionsgenerally can be circumvented byappropriate adjustment of the dosingtimes of the levothyroxine relative tothe binding agents. Add your drug list to My Med List to view medical information in a simple, easy-to-read, personalized format. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. A reproduction study in rats at doses up to 38 times the human dose did not reveal any indication of fertility impairment.

Lansoprazole is used to treat stomach and intestinal ulcers, erosive esophagitis and … Ranitidine is used to treat and prevent ulcers in the stomach and intestines. Ask your doctor before using an antacid, and use only the type your doctor recommends. Some antacids can make it harder for sucralfate to work in your stomach. Avoid taking an antacid within 30 minutes before or after taking Carafate.

Carafate (sucralfate) is an anti-ulcer medication used to treat duodenal ulcers. While this interaction is unlikely to cause significant problems, it could intensify side effects or reduce the effectiveness of one or both medications. Monitoring for changes in symptoms and your condition is recommended, and adjustments may be made if needed to manage any increased or more pronounced side effects. Usually it should be taken at least 30 to 60 minutes before eating breakfast, or at bedtime (3 or more hours after the evening meal).

• Enter medications to view a detailed interaction report using our Drug Interaction Checker.
• Avoid taking any other medications within 2 hours before or after you take Carafate.
• The timing of meals relative to your oral levothyroxine dose can affect the absorption of the medication.
• Provides a detailed discussion on how patients and clinicians can approach the identified drug interaction as well as offers guidance on what to expect and strategies to potentially mitigate the effects of the interaction.

Drug and food interactions

If you are unsure whether one of your medicines interacts with levothyroxine, talk to your doctor or pharmacist. Make sure to always give all of your healthcare providers a full list of your medications (prescription and nonprescription) and any supplements you take. This will help you and your doctors to evaluate all possible interactions and come up with a plan to avoid or minimize them.

Enter medications to view a detailed interaction report using our Drug Interaction Checker. Carafate is not greatly absorbed into the body through the digestive tract. It works mainly in the lining of the stomach by sticking to ulcer sites and protecting them from acids, enzymes, and bile salts. You are encouraged to report negative side effects of prescription drugs to the FDA. These observations suggest that sucralfate’s antiulcer activity is the result of formation of an ulcer- adherent complex that covers the ulcer site and protects it against further attack by acid, pepsin, and bile salts. There are approximately 14 to 16 mEq of acid-neutralizing capacity per 1 g dose of sucralfate.